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Occurrence of Severe Destructive Lyme Arthritis in Hamsters Vaccinated with Outer Surface Protein A and Challenged with Borrelia burgdorferi

Arthritis is a frequent and major complication of infection with Borrelia burgdorferi sensu stricto. The antigens responsible for the induction of arthritis are unknown. Here we provide direct evidence that a major surface protein, outer surface protein A (OspA), can induce arthritis. Hamsters were...

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Autori principali: Croke, Cindy L., Munson, Erik L., Lovrich, Steven D., Christopherson, John A., Remington, Monica C., England, Douglas M., Callister, Steven M., Schell, Ronald F.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2000
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC97189/
https://ncbi.nlm.nih.gov/pubmed/10639430
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