Occurrence of Severe Destructive Lyme Arthritis in Hamsters Vaccinated with Outer Surface Protein A and Challenged with Borrelia burgdorferi

Arthritis is a frequent and major complication of infection with Borrelia burgdorferi sensu stricto. The antigens responsible for the induction of arthritis are unknown. Here we provide direct evidence that a major surface protein, outer surface protein A (OspA), can induce arthritis. Hamsters were...

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Detalhes bibliográficos

Publicado no:	Infect Immun
Principais autores:	Croke, Cindy L., Munson, Erik L., Lovrich, Steven D., Christopherson, John A., Remington, Monica C., England, Douglas M., Callister, Steven M., Schell, Ronald F.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2000
Assuntos:	Microbial Immunity and Vaccines
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC97189/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10639430/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.68.2.658-663.2000
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