Occurrence of Severe Destructive Lyme Arthritis in Hamsters Vaccinated with Outer Surface Protein A and Challenged with Borrelia burgdorferi

Arthritis is a frequent and major complication of infection with Borrelia burgdorferi sensu stricto. The antigens responsible for the induction of arthritis are unknown. Here we provide direct evidence that a major surface protein, outer surface protein A (OspA), can induce arthritis. Hamsters were...

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Main Authors: Croke, Cindy L., Munson, Erik L., Lovrich, Steven D., Christopherson, John A., Remington, Monica C., England, Douglas M., Callister, Steven M., Schell, Ronald F.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2000
Teme:
Microbial Immunity and Vaccines
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC97189/
https://ncbi.nlm.nih.gov/pubmed/10639430
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