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Cleavage of a Recombinant Human Immunoglobulin A2 (IgA2)-IgA1 Hybrid Antibody by Certain Bacterial IgA1 Proteases

To understand more about the factors influencing the cleavage of immunoglobulin A1 (IgA1) by microbial IgA1 proteases, a recombinant human IgA2/IgA1 hybrid molecule was generated. In the hybrid, termed IgA2/A1 half hinge, a seven-amino-acid sequence corresponding to one half of the duplicated sequen...

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Gepubliceerd in:Infect Immun
Hoofdauteurs: Senior, Bernard W., Dunlop, James I., Batten, Margaret R., Kilian, Mogens, Woof, Jenny M.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology (ASM) 2000
Onderwerpen:
Molecular and Cellular Pathogenesis
Online toegang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC97164/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10639405/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.68.2.463-469.2000
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