Immunopathologic Alterations in Murine Models of Sepsis of Increasing Severity

We investigated inflammatory and physiologic parameters in sepsis models of increasing lethality induced by cecal ligation and puncture (CLP). Mice received imipenem for antibiotic therapy, and groups were sacrificed at 2, 4, 8, 12, 16, 20, and 24 h after CLP. The severity of sepsis increased with n...

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Bibliographic Details
Main Authors: Ebong, Samuel, Call, Douglas, Nemzek, Jean, Bolgos, Gerald, Newcomb, David, Remick, Daniel
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 1999
Subjects:
Host Response and Inflammation
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC97073/
https://ncbi.nlm.nih.gov/pubmed/10569781
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