Expression of Recombinant Enterotoxigenic Escherichia coli Colonization Factor Antigen I by Salmonella typhimurium Elicits a Biphasic T Helper Cell Response

Protective immunity to enterotoxigenic Escherichia coli (ETEC) is antibody (Ab) dependent; however, oral immunization with purified ETEC fimbriae fails to elicit protective immunity as a consequence of antigenic alteration by the gastrointestinal (GI) tract. Unless unaltered ETEC fimbriae can reach...

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Autores principales: Pascual, David W., Hone, David M., Hall, Stacy, van Ginkel, Frederik W., Yamamoto, Masafumi, Walters, Nancy, Fujihashi, Kohataro, Powell, Robert J., Wu, Shaoguang, Vancott, John L., Kiyono, Hiroshi, McGhee, Jerry R.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 1999
Materias:
Microbial Immunity and Vaccines
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC97026/
https://ncbi.nlm.nih.gov/pubmed/10569734
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