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Expression of Recombinant Enterotoxigenic Escherichia coli Colonization Factor Antigen I by Salmonella typhimurium Elicits a Biphasic T Helper Cell Response

Protective immunity to enterotoxigenic Escherichia coli (ETEC) is antibody (Ab) dependent; however, oral immunization with purified ETEC fimbriae fails to elicit protective immunity as a consequence of antigenic alteration by the gastrointestinal (GI) tract. Unless unaltered ETEC fimbriae can reach...

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Main Authors: Pascual, David W., Hone, David M., Hall, Stacy, van Ginkel, Frederik W., Yamamoto, Masafumi, Walters, Nancy, Fujihashi, Kohataro, Powell, Robert J., Wu, Shaoguang, Vancott, John L., Kiyono, Hiroshi, McGhee, Jerry R.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 1999
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC97026/
https://ncbi.nlm.nih.gov/pubmed/10569734
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