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Oral immunization with Porphyromonas gingivalis outer membrane protein and CpGoligodeoxynucleotides elicits T helper 1 and 2 cytokines for enhanced protective immunity

The aim of this study was to evaluate the efficacy of an oral vaccine containing the 40-kDa outer membrane protein of Porphyromonas gingivalis (40K OMP) and synthetic oligodeoxynucleotides containing unmethylated CpG dinucleotides (CpG ODN) to control oral infection by P. gingivalis. [run on] 40K-OM...

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Autors principals: Liu, Chenlu, Hashizume, Tomomi, Kurita-Ochiai, Tomoko, Fujihashi, Kohtaro, Yamamoto, Masafumi
Format: Artigo
Idioma:Inglês
Publicat: 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2874939/
https://ncbi.nlm.nih.gov/pubmed/20502628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.2041-1014.2009.00560.x
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