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Nasal Immunization with Porphyromonas gingivalis Outer Membrane Protein Decreases P. gingivalis-Induced Atherosclerosis and Inflammation in Spontaneously Hyperlipidemic Mice

Porphyromonas gingivalis has been shown to accelerate atherosclerotic lesion development in hyperlipidemic animals. We assessed the potential of a nasal vaccine against P. gingivalis infection for the prevention of atherosclerosis. Apolipoprotein E-deficient spontaneously hyperlipidemic (Apoe(shl))...

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Detalhes bibliográficos
Main Authors: Koizumi, Y., Kurita-Ochiai, T., Oguchi, S., Yamamoto, M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2446728/
https://ncbi.nlm.nih.gov/pubmed/18426881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01572-07
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