Expression of Recombinant Enterotoxigenic Escherichia coli Colonization Factor Antigen I by Salmonella typhimurium Elicits a Biphasic T Helper Cell Response

Protective immunity to enterotoxigenic Escherichia coli (ETEC) is antibody (Ab) dependent; however, oral immunization with purified ETEC fimbriae fails to elicit protective immunity as a consequence of antigenic alteration by the gastrointestinal (GI) tract. Unless unaltered ETEC fimbriae can reach...

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Bibliographische Detailangaben
Hauptverfasser: Pascual, David W., Hone, David M., Hall, Stacy, van Ginkel, Frederik W., Yamamoto, Masafumi, Walters, Nancy, Fujihashi, Kohataro, Powell, Robert J., Wu, Shaoguang, Vancott, John L., Kiyono, Hiroshi, McGhee, Jerry R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 1999
Schlagworte:
Microbial Immunity and Vaccines
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC97026/
https://ncbi.nlm.nih.gov/pubmed/10569734
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