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Exposure of N-Formyl-l-Methionyl-l-Leucyl-l-Phenylalanine-Activated Human Neutrophils to the Pseudomonas aeruginosa-Derived Pigment 1-Hydroxyphenazine Is Associated with Impaired Calcium Efflux and Potentiation of Primary Granule Enzyme Release
The effects of pathologically relevant concentrations (0.38 to 12.5 μM) of the proinflammatory, Pseudomonas aeruginosa-derived pigment 1-hydroxyphenazine (1-hp) on Ca(2+) metabolism and intracellular cyclic AMP (cAMP) in N-formyl-l-methionyl-l-leucyl-l-phenylalanine (FMLP; 1 μM)-activated human neut...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
1999
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC96865/ https://ncbi.nlm.nih.gov/pubmed/10496890 |
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