Exposure of N-Formyl-l-Methionyl-l-Leucyl-l-Phenylalanine-Activated Human Neutrophils to the Pseudomonas aeruginosa-Derived Pigment 1-Hydroxyphenazine Is Associated with Impaired Calcium Efflux and Potentiation of Primary Granule Enzyme Release

The effects of pathologically relevant concentrations (0.38 to 12.5 μM) of the proinflammatory, Pseudomonas aeruginosa-derived pigment 1-hydroxyphenazine (1-hp) on Ca(2+) metabolism and intracellular cyclic AMP (cAMP) in N-formyl-l-methionyl-l-leucyl-l-phenylalanine (FMLP; 1 μM)-activated human neut...

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Εκδόθηκε σε:	Infect Immun
Κύριοι συγγραφείς:	Ramafi, Grace, Anderson, Ronald, Theron, Annette, Feldman, Charles, Taylor, Graham W., Wilson, Robert, Cole, Peter J.
Μορφή:	Artigo
Γλώσσα:	Inglês
Έκδοση:	American Society for Microbiology (ASM) 1999
Θέματα:	Host Response and Inflammation
Διαθέσιμο Online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC96865/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10496890/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.67.10.5157-5162.1999
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