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Clostridium botulinum C2 Toxin Delays Entry into Mitosis and Activation of p34(cdc2) Kinase and cdc25-C Phosphatase in HeLa cells

The Clostridium botulinum C2 toxin ADP-ribosylates monomeric actin, thereby inducing disassembly of actin filaments, alteration of focal adhesions, and rounding of cells. After treatment with C2 toxin, cells stop to proliferate but remain viable for about 2 days. In view of reported correlations bet...

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Bibliografische gegevens
Hoofdauteurs: Barth, Holger, Klingler, Manuela, Aktories, Klaus, Kinzel, Volker
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 1999
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC96856/
https://ncbi.nlm.nih.gov/pubmed/10496881
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