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CpG Motifs in Porphyromonas gingivalis DNA Stimulate Interleukin-6 Expression in Human Gingival Fibroblasts

We suggest here that Porphyromonas gingivalis DNA may function as a virulence factor in periodontal disease through expression of inflammatory cytokine. The bacterial DNA markedly stimulated in a dose-dependent manner interleukin-6 (IL-6) production by human gingival fibroblasts. The stimulatory act...

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Sonraí Bibleagrafaíochta
Main Authors: Takeshita, Akira, Imai, Kenichi, Hanazawa, Shigemasa
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Microbiology 1999
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC96750/
https://ncbi.nlm.nih.gov/pubmed/10456872
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