CpG Motifs in Porphyromonas gingivalis DNA Stimulate Interleukin-6 Expression in Human Gingival Fibroblasts

We suggest here that Porphyromonas gingivalis DNA may function as a virulence factor in periodontal disease through expression of inflammatory cytokine. The bacterial DNA markedly stimulated in a dose-dependent manner interleukin-6 (IL-6) production by human gingival fibroblasts. The stimulatory act...

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Detalhes bibliográficos

Publicado no:	Infect Immun
Principais autores:	Takeshita, Akira, Imai, Kenichi, Hanazawa, Shigemasa
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1999
Assuntos:	Host Response and Inflammation
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC96750/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10456872/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.67.9.4340-4345.1999
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