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CpG Motifs in Porphyromonas gingivalis DNA Stimulate Interleukin-6 Expression in Human Gingival Fibroblasts

We suggest here that Porphyromonas gingivalis DNA may function as a virulence factor in periodontal disease through expression of inflammatory cytokine. The bacterial DNA markedly stimulated in a dose-dependent manner interleukin-6 (IL-6) production by human gingival fibroblasts. The stimulatory act...

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Bibliografische gegevens
Gepubliceerd in:Infect Immun
Hoofdauteurs: Takeshita, Akira, Imai, Kenichi, Hanazawa, Shigemasa
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology (ASM) 1999
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC96750/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10456872/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.67.9.4340-4345.1999
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