Fibrinogen Cleavage by the Streptococcus pyogenes Extracellular Cysteine Protease and Generation of Antibodies That Inhibit Enzyme Proteolytic Activity

The extracellular cysteine protease from Streptococcus pyogenes is a virulence factor that plays a significant role in host-pathogen interaction. Streptococcal protease is expressed as an inactive 40-kDa precursor that is autocatalytically converted into a 28-kDa mature (active) enzyme. Replacement...

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Bibliographic Details
Main Authors: Matsuka, Yury V., Pillai, Subramonia, Gubba, Siddeswar, Musser, James M., Olmsted, Stephen B.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 1999
Subjects:
Molecular and Cellular Pathogenesis
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC96748/
https://ncbi.nlm.nih.gov/pubmed/10456870
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