Fibrinogen Cleavage by the Streptococcus pyogenes Extracellular Cysteine Protease and Generation of Antibodies That Inhibit Enzyme Proteolytic Activity

The extracellular cysteine protease from Streptococcus pyogenes is a virulence factor that plays a significant role in host-pathogen interaction. Streptococcal protease is expressed as an inactive 40-kDa precursor that is autocatalytically converted into a 28-kDa mature (active) enzyme. Replacement...

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Vydáno v:	Infect Immun
Hlavní autoři:	Matsuka, Yury V., Pillai, Subramonia, Gubba, Siddeswar, Musser, James M., Olmsted, Stephen B.
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Society for Microbiology (ASM) 1999
Témata:	Molecular and Cellular Pathogenesis
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC96748/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10456870/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.67.9.4326-4333.1999
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