Attenuated Host Resistance against Mycobacterium bovis BCG Infection in Mice Lacking Osteopontin

Expression of the cytokine osteopontin (OPN) is elevated in granulomas caused by Mycobacterium tuberculosis. We tested the hypothesis that OPN contributes to host protection in a mouse model of mycobacterial infection. When infected with Mycobacterium bovis BCG, mice lacking a functional OPN gene ha...

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Bibliografiset tiedot
Päätekijät: Nau, Gerard J., Liaw, Lucy, Chupp, Geoffrey L., Berman, Jeffrey S., Hogan, Brigid L. M., Young, Richard A.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology 1999
Aiheet:
Host Response and Inflammation
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC96728/
https://ncbi.nlm.nih.gov/pubmed/10417195
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