Attenuated Host Resistance against Mycobacterium bovis BCG Infection in Mice Lacking Osteopontin

Expression of the cytokine osteopontin (OPN) is elevated in granulomas caused by Mycobacterium tuberculosis. We tested the hypothesis that OPN contributes to host protection in a mouse model of mycobacterial infection. When infected with Mycobacterium bovis BCG, mice lacking a functional OPN gene ha...

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Detalhes bibliográficos
Main Authors: Nau, Gerard J., Liaw, Lucy, Chupp, Geoffrey L., Berman, Jeffrey S., Hogan, Brigid L. M., Young, Richard A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 1999
Assuntos:
Host Response and Inflammation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC96728/
https://ncbi.nlm.nih.gov/pubmed/10417195
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