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Attenuated Host Resistance against Mycobacterium bovis BCG Infection in Mice Lacking Osteopontin

Expression of the cytokine osteopontin (OPN) is elevated in granulomas caused by Mycobacterium tuberculosis. We tested the hypothesis that OPN contributes to host protection in a mouse model of mycobacterial infection. When infected with Mycobacterium bovis BCG, mice lacking a functional OPN gene ha...

詳細記述

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書誌詳細
主要な著者: Nau, Gerard J., Liaw, Lucy, Chupp, Geoffrey L., Berman, Jeffrey S., Hogan, Brigid L. M., Young, Richard A.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 1999
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC96728/
https://ncbi.nlm.nih.gov/pubmed/10417195
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