Triplex formation by morpholino oligodeoxyribonucleotides in the HER-2/neu promoter requires the pyrimidine motif

Triplex-forming oligonucleotides (TFOs) are good candidates to be used as site-specific DNA-binding agents. Two obstacles encountered with TFOs are susceptibility to nuclease activity and a requirement for magnesium for triplex formation. Morpholino oligonucleotides were shown in one study to form t...

ver descrição completa

Detalhes bibliográficos

Publicado no:	Nucleic Acids Res
Principais autores:	Basye, Jenny, Trent, John O., Gao, Daquan, Ebbinghaus, Scot W.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Oxford University Press 2001
Assuntos:	Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC96684/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11726697/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/29.23.4873
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!