Triplex formation by morpholino oligodeoxyribonucleotides in the HER-2/neu promoter requires the pyrimidine motif

Triplex-forming oligonucleotides (TFOs) are good candidates to be used as site-specific DNA-binding agents. Two obstacles encountered with TFOs are susceptibility to nuclease activity and a requirement for magnesium for triplex formation. Morpholino oligonucleotides were shown in one study to form t...

Täydet tiedot

Bibliografiset tiedot

Julkaisussa:	Nucleic Acids Res
Päätekijät:	Basye, Jenny, Trent, John O., Gao, Daquan, Ebbinghaus, Scot W.
Aineistotyyppi:	Artigo
Kieli:	Inglês
Julkaistu:	Oxford University Press 2001
Aiheet:	Article
Linkit:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC96684/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11726697/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/29.23.4873
Tagit:	Lisää tagi Ei tageja, Lisää ensimmäinen tagi!