Pneumolysin, a Protein Toxin of Streptococcus pneumoniae, Induces Nitric Oxide Production from Macrophages

Nitric oxide (NO) production by inducible NO synthase (iNOS) during inflammation is an essential element of antimicrobial immunity but can also contribute to host-induced tissue damage. Under conditions of bacterial sepsis, large amounts of NO are produced, causing hypotension, a critical pathologic...

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Bibliographic Details
Main Authors: Braun, Johann S., Novak, Rodger, Gao, Geli, Murray, Peter J., Shenep, Jerry L.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 1999
Subjects:
Host Response and Inflammation
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC96649/
https://ncbi.nlm.nih.gov/pubmed/10417133
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