In Vivo Expression and Immunoadjuvancy of a Mutant of Heat-Labile Enterotoxin of Escherichia coli in Vaccine and Vector Strains of Vibrio cholerae

Vibrio cholerae secretes cholera toxin (CT) and the closely related heat-labile enterotoxin (LT) of Escherichia coli, the latter when expressed in V. cholerae. Both toxins are also potent immunoadjuvants. Mutant LT molecules that retain immunoadjuvant properties while possessing markedly diminished...

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Publié dans:	Infect Immun
Auteurs principaux:	Ryan, Edward T., Crean, Thomas I., John, Manohar, Butterton, Joan R., Clements, John D., Calderwood, Stephen B.
Format:	Artigo
Langue:	Inglês
Publié:	American Society for Microbiology (ASM) 1999
Sujets:	Microbial Immunity and Vaccines
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC96516/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10085006/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.67.4.1694-1701.1999
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