In Vitro and In Vivo Analyses of Constitutive and In Vivo-Induced Promoters in Attenuated Vaccine and Vector Strains of Vibrio cholerae

The optimal promoter for in vivo expression of heterologous antigens by live, attenuated vaccine vector strains of Vibrio cholerae is unclear; in vitro analyses of promoter activity may not accurately predict expression of antigens in vivo. We therefore introduced plasmids expressing the B subunit o...

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Bibliographic Details
Main Authors: John, Manohar, Crean, Thomas I., Calderwood, Stephen B., Ryan, Edward T.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2000
Subjects:
Microbial Immunity and Vaccines
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC97263/
https://ncbi.nlm.nih.gov/pubmed/10678922
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