Safety and Immunogenicity of a Pseudomonas aeruginosa Hybrid Outer Membrane Protein F-I Vaccine in Human Volunteers

A hybrid protein [Met-Ala-(His)(6)OprF(190–342)-OprI(21–83)] consisting of the mature outer membrane protein I (OprI) and amino acids 190 to 342 of OprF of Pseudomonas aeruginosa was expressed in Escherichia coli and purified by Ni(2+) chelate-affinity chromatography. After safety and pyrogenicity e...

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Main Authors: Mansouri, Erfan, Gabelsberger, Josef, Knapp, Bernhard, Hundt, Erika, Lenz, Uwe, Hungerer, Klaus-Dieter, Gilleland, Harry E., Staczek, John, Domdey, Horst, von Specht, Bernd-Ulrich
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 1999
Assuntos:
Microbial Immunity and Vaccines
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC96482/
https://ncbi.nlm.nih.gov/pubmed/10024596
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