Safety and Immunogenicity of a Pseudomonas aeruginosa Hybrid Outer Membrane Protein F-I Vaccine in Human Volunteers

A hybrid protein [Met-Ala-(His)(6)OprF(190–342)-OprI(21–83)] consisting of the mature outer membrane protein I (OprI) and amino acids 190 to 342 of OprF of Pseudomonas aeruginosa was expressed in Escherichia coli and purified by Ni(2+) chelate-affinity chromatography. After safety and pyrogenicity e...

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Pubblicato in:	Infect Immun
Autori principali:	Mansouri, Erfan, Gabelsberger, Josef, Knapp, Bernhard, Hundt, Erika, Lenz, Uwe, Hungerer, Klaus-Dieter, Gilleland, Harry E., Staczek, John, Domdey, Horst, von Specht, Bernd-Ulrich
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1999
Soggetti:	Microbial Immunity and Vaccines
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC96482/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10024596/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.67.3.1461-1470.1999
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