Safety and Immunogenicity of a Pseudomonas aeruginosa Hybrid Outer Membrane Protein F-I Vaccine in Human Volunteers
A hybrid protein [Met-Ala-(His)(6)OprF(190–342)-OprI(21–83)] consisting of the mature outer membrane protein I (OprI) and amino acids 190 to 342 of OprF of Pseudomonas aeruginosa was expressed in Escherichia coli and purified by Ni(2+) chelate-affinity chromatography. After safety and pyrogenicity e...
Guardat en:
| Publicat a: | Infect Immun |
|---|---|
| Autors principals: | , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Microbiology (ASM)
1999
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC96482/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10024596/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.67.3.1461-1470.1999 |
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