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Cryptococcus neoformans Resides in an Acidic Phagolysosome of Human Macrophages

Recently, we demonstrated that human monocyte-derived macrophages (MDM) treated with chloroquine or ammonium chloride had markedly increased antifungal activity against the AIDS-related pathogen Cryptococcus neoformans. Both of these agents raise the lysosomal pH, which suggested that the increased...

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Vydáno v:Infect Immun
Hlavní autoři: Levitz, Stuart M., Nong, Shu-Hua, Seetoo, Kurt F., Harrison, Thomas S., Speizer, Robert A., Simons, Elizabeth R.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 1999
Témata:
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC96400/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9916104/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.67.2.885-890.1999
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