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Cryptococcus neoformans Resides in an Acidic Phagolysosome of Human Macrophages

Recently, we demonstrated that human monocyte-derived macrophages (MDM) treated with chloroquine or ammonium chloride had markedly increased antifungal activity against the AIDS-related pathogen Cryptococcus neoformans. Both of these agents raise the lysosomal pH, which suggested that the increased...

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Bibliografiske detaljer
Main Authors: Levitz, Stuart M., Nong, Shu-Hua, Seetoo, Kurt F., Harrison, Thomas S., Speizer, Robert A., Simons, Elizabeth R.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 1999
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC96400/
https://ncbi.nlm.nih.gov/pubmed/9916104
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