Streptococcal Pyrogenic Exotoxin B Induces Apoptosis and Reduces Phagocytic Activity in U937 Cells

Treatment of U937 human monocyte-like cells with Streptococcus pyogenes led to an induction of apoptosis in these cells. A comparison between the wild-type strain and its isogenic protease-negative mutant indicated that the production of streptococcal pyrogenic exotoxin B (SPE B), a cysteine proteas...

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Main Authors: Kuo, Chih-Feng, Wu, Jiunn-Jong, Tsai, Pei-Jane, Kao, Fu-Jen, Lei, Huan-Yao, Lin, Ming T., Lin, Yee-Shin
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 1999
Assuntos:
Bacterial Infections
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC96287/
https://ncbi.nlm.nih.gov/pubmed/9864206
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