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Toxoids of Streptococcal Pyrogenic Exotoxin A Are Protective in Rabbit Models of Streptococcal Toxic Shock Syndrome

Streptococcal pyrogenic exotoxins (SPEs) are superantigens that have been implicated in causing streptococcal toxic shock syndrome (STSS). Most notably, SPE serotype A is made by nearly all M-protein serotype 1 and 3 streptococci, the M types most associated with the illness (these strains contain o...

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Main Authors: Roggiani, Manuela, Stoehr, Jennifer A., Olmsted, Stephen B., Matsuka, Yury V., Pillai, Subramonia, Ohlendorf, Douglas H., Schlievert, Patrick M.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2000
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Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC101724/
https://ncbi.nlm.nih.gov/pubmed/10948118
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