Streptococcal Pyrogenic Exotoxin B Induces Apoptosis and Reduces Phagocytic Activity in U937 Cells

Treatment of U937 human monocyte-like cells with Streptococcus pyogenes led to an induction of apoptosis in these cells. A comparison between the wild-type strain and its isogenic protease-negative mutant indicated that the production of streptococcal pyrogenic exotoxin B (SPE B), a cysteine proteas...

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Veröffentlicht in:	Infect Immun
Hauptverfasser:	Kuo, Chih-Feng, Wu, Jiunn-Jong, Tsai, Pei-Jane, Kao, Fu-Jen, Lei, Huan-Yao, Lin, Ming T., Lin, Yee-Shin
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1999
Schlagworte:	Bacterial Infections
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC96287/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9864206/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.67.1.126-130.1999
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