STAT4 Is Required for Antibacterial Defense but Enhances Mortality during Polymicrobial Sepsis

The signal transducer and activator of transcription factor 4 (STAT4) pathway mediates the intracellular effects of interleukin-12 (IL-12), leading to the production of gamma interferon, induction of a T helper type 1 response, and increased natural killer cell cytotoxicity. The purpose of this stud...

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Detalhes bibliográficos
Main Authors: Godshall, Christopher J., Lentsch, Alex B., Peyton, James C., Scott, Melanie J., Cheadle, William G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Immune-Mediated Responses and Disorders
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC96223/
https://ncbi.nlm.nih.gov/pubmed/11687437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CDLI.8.6.1044-1048.2001
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