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IRAK1-dependent signaling mediates mortality in polymicrobial sepsis
IRAK1 is a key regulatory protein in TLR/IL1R-mediated cell activation during the inflammatory response. Studies indicated that pending on the nature of the used inflammatory model, down-regulation of IRAK1 may be beneficial or detrimental. However the role of IRAK1 in affecting outcome in polymicro...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3823648/ https://ncbi.nlm.nih.gov/pubmed/23856940 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10753-013-9692-1 |
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