Suppression of Endotoxin- and Staphylococcal Exotoxin-Induced Cytokines and Chemokines by a Phospholipase C Inhibitor in Human Peripheral Blood Mononuclear Cells

Excessive release of proinflammatory cytokines from cells stimulated with lipopolysaccharide (LPS) or staphylococcal exotoxin (SE) mediates the pathophysiologic manifestations of septic shock. Tricyclodecan-9-yl (D609), an inhibitor of phosphatidylcholine-specific phospholipase C, suppressed LPS- or...

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Publié dans:	Clin Diagn Lab Immunol
Auteur principal:	Krakauer, Teresa
Format:	Artigo
Langue:	Inglês
Publié:	American Society for Microbiology (ASM) 2001
Sujets:	Antibodies and Mediators of Immunity
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC96079/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11238238/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/CDLI.8.2.449-453.2001
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