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Suppression of Endotoxin- and Staphylococcal Exotoxin-Induced Cytokines and Chemokines by a Phospholipase C Inhibitor in Human Peripheral Blood Mononuclear Cells
Excessive release of proinflammatory cytokines from cells stimulated with lipopolysaccharide (LPS) or staphylococcal exotoxin (SE) mediates the pathophysiologic manifestations of septic shock. Tricyclodecan-9-yl (D609), an inhibitor of phosphatidylcholine-specific phospholipase C, suppressed LPS- or...
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Microbiology
2001
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| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC96079/ https://ncbi.nlm.nih.gov/pubmed/11238238 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CDLI.8.2.449-453.2001 |
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