Positive Selection of Mutations Leading to Loss or Reduction of Transcriptional Activity of PrfA, the Central Regulator of Listeria monocytogenes Virulence
Transcription factor PrfA controls the expression of virulence genes essential for Listeria monocytogenes pathogenesis. To gain insight into the structure-function relationship of PrfA, we devised a positive-selection system to isolate mutations reducing or abolishing transcriptional activity. The s...
Kaydedildi:
| Yayımlandı: | J Bacteriol |
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| Asıl Yazarlar: | , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
American Society for Microbiology (ASM)
2001
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC95447/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11544218/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JB.183.19.5562-5570.2001 |
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