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Gene Replacement Analysis of the Butyrolactone Autoregulator Receptor (FarA) Reveals that FarA Acts as a Novel Regulator in Secondary Metabolism of Streptomyces lavendulae FRI-5

IM-2 [(2R,3R,1′R)-2-1′-hydroxybutyl-3-hydroxymethyl γ-butanolide] is a γ-butyrolactone autoregulator which, in Streptomyces lavendulae FRI-5, switches off the production of d-cycloserine but switches on the production of a blue pigment and several nucleoside antibiotics. To clarify the in vivo funct...

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Detalhes bibliográficos
Main Authors: Kitani, Shigeru, Yamada, Yasuhiro, Nihira, Takuya
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC95326/
https://ncbi.nlm.nih.gov/pubmed/11418577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.183.14.4357-4363.2001
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