Gene Replacement Analysis of the Streptomyces virginiae barA Gene Encoding the Butyrolactone Autoregulator Receptor Reveals that BarA Acts as a Repressor in Virginiamycin Biosynthesis

Virginiae butanolides (VBs), which are among the butyrolactone autoregulators of Streptomyces species, act as a primary signal in Streptomyces virginiae to trigger virginiamycin biosynthesis and possess a specific binding protein, BarA. To clarify the in vivo function of BarA in the VB-mediated sign...

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Bibliographic Details
Main Authors: Nakano, Hiroko, Takehara, Emio, Nihira, Takuya, Yamada, Yasuhiro
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 1998
Subjects:
Genetics and Molecular Biology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC107284/
https://ncbi.nlm.nih.gov/pubmed/9642182
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