In Vitro Analysis of the Butyrolactone Autoregulator Receptor Protein (FarA) of Streptomyces lavendulae FRI-5 Reveals that FarA Acts as a DNA-Binding Transcriptional Regulator That Controls Its Own Synthesis

FarA of Streptomyces lavendulae FRI-5 is a specific receptor protein for IM-2, a butyrolactone autoregulator that controls the production of a blue pigment and the nucleoside antibiotics showdomycin and minimycin. Gel shift assays demonstrated that FarA binds to the farA upstream region and that thi...

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Bibliographic Details
Main Authors: Kitani, Shigeru, Kinoshita, Hiroshi, Nihira, Takuya, Yamada, Yasuhiro
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 1999
Subjects:
Genetics and Molecular Biology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC93999/
https://ncbi.nlm.nih.gov/pubmed/10438782
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