Gene Replacement Analysis of the Butyrolactone Autoregulator Receptor (FarA) Reveals that FarA Acts as a Novel Regulator in Secondary Metabolism of Streptomyces lavendulae FRI-5

IM-2 [(2R,3R,1′R)-2-1′-hydroxybutyl-3-hydroxymethyl γ-butanolide] is a γ-butyrolactone autoregulator which, in Streptomyces lavendulae FRI-5, switches off the production of d-cycloserine but switches on the production of a blue pigment and several nucleoside antibiotics. To clarify the in vivo funct...

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הוצא לאור ב:	J Bacteriol
Principais autores:	Kitani, Shigeru, Yamada, Yasuhiro, Nihira, Takuya
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	American Society for Microbiology (ASM) 2001
נושאים:	Genetics and Molecular Biology
גישה מקוונת:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC95326/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11418577/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JB.183.14.4357-4363.2001
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