Identification of Escherichia coli dnaE (polC) Mutants with Altered Sensitivity to 2′,3′-Dideoxyadenosine
Bacteria with reduced DNA polymerase I activity have increased sensitivity to killing by chain-terminating nucleotides (S. A. Rashbaum and N. R. Cozzarelli, Nature 264:679–680, 1976). We have used this observation as the basis of a genetic strategy to identify mutations in the dnaE (polC) gene of Es...
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| Publicado en: | J Bacteriol |
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| Autores principales: | , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
American Society for Microbiology (ASM)
2000
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC94578/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10869071/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.182.14.3942-3947.2000 |
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