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Identification of Escherichia coli dnaE (polC) Mutants with Altered Sensitivity to 2′,3′-Dideoxyadenosine

Bacteria with reduced DNA polymerase I activity have increased sensitivity to killing by chain-terminating nucleotides (S. A. Rashbaum and N. R. Cozzarelli, Nature 264:679–680, 1976). We have used this observation as the basis of a genetic strategy to identify mutations in the dnaE (polC) gene of Es...

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Sábháilte in:
Sonraí bibleagrafaíochta
Foilsithe in:J Bacteriol
Príomhchruthaitheoirí: Hiratsuka, Koji, Reha-Krantz, Linda J.
Formáid: Artigo
Teanga:Inglês
Foilsithe / Cruthaithe: American Society for Microbiology (ASM) 2000
Ábhair:
Rochtain ar líne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC94578/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10869071/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.182.14.3942-3947.2000
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