Identification of Escherichia coli dnaE (polC) Mutants with Altered Sensitivity to 2′,3′-Dideoxyadenosine
Bacteria with reduced DNA polymerase I activity have increased sensitivity to killing by chain-terminating nucleotides (S. A. Rashbaum and N. R. Cozzarelli, Nature 264:679–680, 1976). We have used this observation as the basis of a genetic strategy to identify mutations in the dnaE (polC) gene of Es...
שמור ב:
| הוצא לאור ב: | J Bacteriol |
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| Principais autores: | , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
American Society for Microbiology (ASM)
2000
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC94578/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10869071/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.182.14.3942-3947.2000 |
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