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Use of Heme Compounds as Iron Sources by Pathogenic Neisseriae Requires the Product of the hemO Gene

Heme compounds are an important source of iron for neisseriae. We have identified a neisserial gene, hemO, that is essential for heme, hemoglobin (Hb), and haptoglobin-Hb utilization. The hemO gene is located 178 bp upstream of the hmbR Hb receptor gene in Neisseria meningitidis isolates. The produc...

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Détails bibliographiques
Publié dans:J Bacteriol
Auteurs principaux: Zhu, Wenming, Hunt, Desiree J., Richardson, Anthony R., Stojiljkovic, Igor
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology (ASM) 2000
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC94294/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10629191/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.182.2.439-447.2000
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