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Use of Heme Compounds as Iron Sources by Pathogenic Neisseriae Requires the Product of the hemO Gene

Heme compounds are an important source of iron for neisseriae. We have identified a neisserial gene, hemO, that is essential for heme, hemoglobin (Hb), and haptoglobin-Hb utilization. The hemO gene is located 178 bp upstream of the hmbR Hb receptor gene in Neisseria meningitidis isolates. The produc...

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Detalhes bibliográficos
Main Authors: Zhu, Wenming, Hunt, Desiree J., Richardson, Anthony R., Stojiljkovic, Igor
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2000
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC94294/
https://ncbi.nlm.nih.gov/pubmed/10629191
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