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Homologues of Neisserial Heme Oxygenase in Gram-Negative Bacteria: Degradation of Heme by the Product of the pigA Gene of Pseudomonas aeruginosa

The oxidative cleavage of heme to release iron is a mechanism by which some bacterial pathogens can utilize heme as an iron source. The pigA gene of Pseudomonas aeruginosa is shown to encode a heme oxygenase protein, which was identified in the genome sequence by its significant homology (37%) with...

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Autors principals: Ratliff, Melanie, Zhu, Wenming, Deshmukh, Rahul, Wilks, Angela, Stojiljkovic, Igor
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2001
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC100135/
https://ncbi.nlm.nih.gov/pubmed/11591684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.183.21.6394-6403.2001
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