Imbalanced Base Excision Repair Increases Spontaneous Mutation and Alkylation Sensitivity in Escherichia coli

Inappropriate expression of 3-methyladenine (3MeA) DNA glycosylases has been shown to have harmful effects on microbial and mammalian cells. To understand the underlying reasons for this phenomenon, we have determined how DNA glycosylase activity and substrate specificity modulate glycosylase effect...

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Detalles Bibliográficos

Publicado en:	J Bacteriol
Principais autores:	Posnick, Lauren M., Samson, Leona D.
Formato:	Artigo
Idioma:	Inglês
Publicado:	American Society for Microbiology (ASM) 1999
Assuntos:	Genetics and Molecular Biology
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC94142/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10542179/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.181.21.6763-6771.1999
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