DNA alkylation repair limits spontaneous base substitution mutations in Escherichia coli.

The Escherichia coli Ada and Ogt DNA methyltransferases (MTases) are known to transfer simple alkyl groups from O6-alkylguanine and O4-alkylthymine, directly restoring these alkylated DNA lesions to guanine and thymine. In addition to being exquisitely sensitive to the mutagenic effects of methylati...

Descrición completa

Detalles Bibliográficos

Publicado en:	J Bacteriol
Principais autores:	Mackay, W J, Han, S, Samson, L D
Formato:	Artigo
Idioma:	Inglês
Publicado:	American Society for Microbiology (ASM) 1994
Assuntos:	Research Article
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC205492/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8195077/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.176.11.3224-3230.1994
Tags:	Engadir etiqueta Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!