DNA alkylation repair limits spontaneous base substitution mutations in Escherichia coli.
The Escherichia coli Ada and Ogt DNA methyltransferases (MTases) are known to transfer simple alkyl groups from O6-alkylguanine and O4-alkylthymine, directly restoring these alkylated DNA lesions to guanine and thymine. In addition to being exquisitely sensitive to the mutagenic effects of methylati...
Zapisane w:
| Wydane w: | J Bacteriol |
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| Główni autorzy: | , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
American Society for Microbiology (ASM)
1994
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC205492/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8195077/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.176.11.3224-3230.1994 |
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